An Endonuclease from Neurospora Crassa Specific for Polynucleotides Lacking an Ordered Structure. Ii. Studies of Enzyme Specificity.

نویسندگان

  • S LINN
  • I R LEHMAN
چکیده

The preceding paper described the purification and some of the properties of a nuclease from Neurospora crussa (1). The purpose of this communication is to describe its mode of attack as an endonuclease with a high degree of specificity for polynucleotides (both riboand deoxyribo-) lacking an ordered structure. Moreover, it has a distinct preference for diester bonds within a polynucleotide in which guanine residues are involved.

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An Endonuclease from Neurospora crassa Specific for Polynucleotides Lacking an Ordered Structure

The preceding paper described the purification and some of the properties of a nuclease from Neurospora crussa (1). The purpose of this communication is to describe its mode of attack as an endonuclease with a high degree of specificity for polynucleotides (both riboand deoxyribo-) lacking an ordered structure. Moreover, it has a distinct preference for diester bonds within a polynucleotide in ...

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عنوان ژورنال:
  • The Journal of biological chemistry

دوره 240  شماره 

صفحات  -

تاریخ انتشار 1965